Philadelphia chromosome
基本解释
- [遗] 费城染色体
英汉例句
- The Philadelphia chromosome (universally present in CML) is lacking in patients with leukemoid reactions.
费城染色体(一般出现在CML)在白血病样反应中一般不出现。
www.goo--gle.com - Philadelphia chromosome formed may result in the generation of the fusion protein BCR ABL, a constitutively activated tyrosine ki nas e which then causes chronic myeloid leukemia (CML).
慢性粒细胞白血病(CML)患者体内有异常染色体形成并产生BCR ABL融合蛋白,该融合蛋白能激活酪氨酸激酶,刺激细胞过度增生导致慢性粒细胞白血病的发生。 - The drug was originally developed as Imatinib using rational drug design after Philadelphia chromosome mutation was discovered.
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双语例句
权威例句
词组短语
- Philadelphia Chromosome -Positive 费城染色体阳性
- Philadelphia chromosome 1 费城染色体
短语
专业释义
- 费城染色体
It is observed that besides the Philadelphia chromosome, more than 80% patients have genetical and chromosomal abnormalities such as the triploidy of 8, 19 chromosomes, while at the molecular level, p53 gene mutation occurs, whose mechanism is still unclear nowadays.
急变期出现除费城染色体以外的遗传学和染色体的改变,如染色体8和19的三倍体,而在分子水平出现p53基因的突变,其机理目前尚不清楚。生物学
- 费城染色体