allosteric activator

基本解释

Cyclin D1 which functions as a mitogenic sensor and allosteric activator of CDK4/6, is one of the more frequently altered cell cycle regulators in cancers.
细胞周期蛋白D1作为一个能促进有丝分裂和CDK4的变构激活剂，是癌症中较频繁变化的细胞周期调节子。
Phosphorylation leads to inactivation of GS, but activity is restored by the binding of the allosteric activator glucose-6-phosphate, which induces its dephosphorylation and activation (4).
磷酸化会抑制GS活性，但活性可被变异配体6-磷酸葡萄糖结合后恢复，6-磷酸葡萄糖可以诱导GS的去磷酸化从而激活。
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